Increased excitation-inhibition balance and a loss of GABAergic synapses in the serine racemase knockout model of NMDA receptor hypofunction

Congrats to Shekib for his first Gray Lab publication! There is substantial evidence that both NMDA receptor (NMDAR) hypofunction and dysfunction of GABAergic neurotransmission contribute to schizophrenia, though the relationship between these pathophysiological processes remains poorly understood. Here, we used